144060-72-0

Upstream product

• 20582-55-2 ethyl 4-methylthiazole-5-carboxylate 
• 1365938-79-9 4-bromo-1-(2,2-dimethylpropoxy)-2-nitrobenzene 
• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 
• 75-84-3 2,2-dimethyl-propanol-1 

Downstream Products

• 144060-54-8 2-(3-Cyano-4-neopentyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid 

Relevant academic research and scientific papers

CRYSTAL OF AZOLE BENZENE DERIVATIVE

There are provided crystals of 2-[4-(2,2-dimethylpropoxy)-3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid which is useful as a therapeutic agent or prophylactic agent for gout, hyperuricemia and the like.

2-arylthiazole derivatives and pharmaceutical composition thereof

Pharmaceutical compositions for treating gout or hyperuricemia and containing a new categorized compound, i.e. 2-arylthiazole derivatives, as an active ingredient, are provided. The 2-arylthiazole derivatives in the present invention are represented by the following formula (I): STR1 wherein Ar is an unsubstituted or substituted pyridyl, thienyl, furyl, naphthyl or phenyl group; X is a hydrogen atom, alkyl group or carboxyl group which may be protected, and Y is a hydrogen atom, alkyl group, or a hydroxyl or carbonyl group which may be protected. Furthermore, novel compounds included in the 2-arylthiazole derivatives and pharmaceutically acceptable salts thereof are provided.