144068-33-7Relevant academic research and scientific papers
Synthesis of the C6-C14 Fragment of Euphosalicin
Aichinger, Christian,Mulzer, Johann,Rinner, Uwe
, p. 1852 - 1856 (2015/08/06)
The synthesis of the C6-C14 fragment of euphosalicin, a highly oxygenated modified jatrophane diterpene, is described. Key steps in the preparation of this versatile intermediate are an Ireland-Claisen rearrangement and a Shibasaki direct asymmetric aldol reaction.
Thiazole sulfonamide compounds for the treatment of neurodegenerative disorders
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Page/Page column 14-15, (2010/02/14)
The present invention relates to compounds of the Formula: wherein R1 to R6, X, Z and A are as defined. These compounds have activity inhibiting production of Aβ-peptide. The invention also relates to pharmaceutical compositions and
A Practical Convergent Route to (23S,25R)-1α,25-Dihydroxyvitamin D3 26,23-Lactone
Hatakeyama, Susumi,Sugawara, Makiko,Kawamura, Mitsuhiro,Takano, Seiichi
, p. 1229 - 1231 (2007/10/02)
The Ireland-Claisen rearrangement of the lactate 8, prepared from the Inhoffen-Lythgoe diol 5, followed by iodolactonisation allowed easy access to the C-D-ring fragment 4, from which a novel convergent synthesis of (23S,25R)-1α,25-dihydroxyvitamin D
