144068-37-1

Basic information

• Product Name: (3R,5S)-5-{(1R,2S)-2-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-1-iodo-propyl}-3-(4-methoxy-benzyloxy)-3-methyl-dihydro-furan-2-one
• CAS NO: 144068-37-1
• Molecular Weight: 670.744
• Mol File: 144068-37-1.mol

Chemical Properties

• CAS DataBase Reference: (3R,5S)-5-{(1R,2S)-2-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-1-iodo-propyl}-3-(4-methoxy-benzyloxy)-3-methyl-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5S)-5-{(1R,2S)-2-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-1-iodo-propyl}-3-(4-methoxy-benzyloxy)-3-methyl-dihydro-furan-2-one(144068-37-1)
• EPA Substance Registry System: (3R,5S)-5-{(1R,2S)-2-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-1-iodo-propyl}-3-(4-methoxy-benzyloxy)-3-methyl-dihydro-furan-2-one(144068-37-1)

Safety Data

• Hazardous Substances Data: 144068-37-1(Hazardous Substances Data)

Upstream product

• 144068-34-8 2-(4-Methoxy-benzyloxy)-propionic acid (S)-1-{(S)-1-[(1R,3aR,4S,7aR)-4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-ethyl}-allyl ester 
• 93489-72-6 [1R-[1β,[αS*,βS*],3aα,4aβ,7aβ]]-octahydro-β,7a-dimethyl-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-α-ethenyl-1H-indene-1-ethanol 
• 144068-36-0 (E)-(R)-6-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-2-(4-methoxy-benzyloxy)-2-methyl-hept-4-enoic acid 

Downstream Products

• 144068-36-0 (E)-(R)-6-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-2-(4-methoxy-benzyloxy)-2-methyl-hept-4-enoic acid 

Relevant articles and documents

A Practical Convergent Route to (23S,25R)-1α,25-Dihydroxyvitamin D3 26,23-Lactone

The Ireland-Claisen rearrangement of the lactate 8, prepared from the Inhoffen-Lythgoe diol 5, followed by iodolactonisation allowed easy access to the C-D-ring fragment 4, from which a novel convergent synthesis of (23S,25R)-1α,25-dihydroxyvitamin D