1440747-52-3Relevant academic research and scientific papers
Lithium Diisopropylamide Catalyzed Allylic C-H Bond Alkylation with Styrenes
Zhang, Xiang-Yu,Zheng, Lei,Guan, Bing-Tao
supporting information, p. 7177 - 7181 (2018/11/25)
Allylic substitution reactions, a well-established approach for new bond construction, often need transition-metal catalysts and stoichiometric amounts of organometallic reagents, strong bases, or oxidants. Lithium diisopropylamide (LDA), a widely used and commercially available Br?nsted base, is herein reported to catalyze the allylic C-H bond addition of 1,3-diarylpropenes to styrenes. Preliminary mechanism studies have provided a solid structure of the π-allyllithium intermediate and revealed the unique catalytic roles of LDA and its conjugate acid diisopropylamine.
Copper-catalyzed oxidative heck reactions between alkyltrifluoroborates and vinyl arenes
Liwosz, Timothy W.,Chemler, Sherry R.
supporting information, p. 3034 - 3037 (2013/07/26)
We report herein that potassium alkyltrifluoroborates can be utilized in oxidative Heck-type reactions with vinyl arenes. The reaction is catalyzed by a Cu(OTf)2/1,10-phenanthroline with MnO2 as the stoichiometric oxidant. In addition to the alkyl Heck, amination, esterification, and dimerization reactions of alkyltrifluoroborates are demonstrated under analogous reaction conditions. Evidence for an alkyl radical intermediate is presented.
