1440958-01-9

Upstream product

• 100-39-0 benzyl bromide 
• 1440957-95-8 3-(1-benzyl-1H-indol-3-yl)-3-chloro-2-propenenitrile 
• 1440957-93-6 3-(1-benzyl-1H-indol-3-yl)-3-chloro-2-propenal oxime 
• 93315-38-9 3-acetyl-1-benzyl-1H-indole 
• 703-80-0 3-acetylindole 

Downstream Products

• 1440957-70-9 6-(1-benzyl-1H-indol-3-yl)-2-(1-piperidinylmethyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1440957-71-0 6-(1-benzyl-1H-indol-3-yl)-2-(4-morpholinylmethyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1440957-72-1 6-(1-benzyl-1H-indol-3-yl)-2-[(4-methyl-1-piperazinyl)methyl]thieno[3,2-d]pyrimidin-4(3H)-one 
• 1440957-73-2 6-(1-benzyl-1H-indol-3-yl)-2-[(4-benzyl-1-piperazinyl)methyl]thieno[3,2-d]pyrimidin-4(3H)-one 
• 1440957-74-3 6-(1-benzyl-1H-indol-3-yl)-2-(1-pyrrolidinylmethyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1440958-15-5 5-(1-benzyl-1H-indol-3-yl)-3-[(1-piperidinylacetyl)amino]-2-thiophenecarboxamide 
• 1440958-16-6 5-(1-benzyl-1H-indol-3-yl)-3-[(4-morpholinylacetyl)amino]-2-thiophenecarboxamide 
• 1440958-17-7 5-(1-benzyl-1H-indol-3-yl)-3-{[(4-methyl-1-piperazinyl)acetyl]amino}-2-thiophene-carboxamide 
• 1440958-18-8 5-(1-benzyl-1H-indol-3-yl)-3-{[(4-benzyl-1-piperazinyl)acetyl]amino}-2-thiophenecarboxamide 
• 1440958-19-9 5-(1-benzyl-1H-indol-3-yl)-3-[(1-pyrrolidinylacetyl)amino]-2-thiophenecarboxamide 
• 1440958-08-6 5-(1-benzyl-1H-indol-3-yl)-3-[(chloroacetyl)amino]-2-thiophenecarboxamide 
• 1440957-75-4 6-(1-benzyl-1H-indol-3-yl)-2-hexylthieno[3,2-d]pyrimidin-4-ol 
• 1440957-76-5 6-(1-benzyl-1H-indol-3-yl)-2-(4-methoxyphenyl)thieno[3,2-d]pyrimidin-4-ol 
• 1440957-77-6 6-(1-benzyl-1H-indol-3-yl)-2-(3,4,5-trimethoxyphenyl)thieno[3,2-d]pyrimidin-4-ol 

Relevant academic research and scientific papers

Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2)

Driven by a multidisciplinary approach combination (Structure-Based (SB) Three-Dimensional Quantitative Structure-Activity Relationships (3-D QSAR), molecular modeling, organic chemistry and various biological evaluations) here is reported the disclosure