1440976-29-3Relevant articles and documents
A Csp3-Csp3 bond forming reductive condensation of α-keto esters and enolizable carbon pronucleophiles
Zhao, Wei,Fink, Darla M.,Labutta, Carolyn A.,Radosevich, Alexander T.
supporting information, p. 3090 - 3093 (2013/07/26)
The preparation of densely functionalized unsymmetrical 1,4-dicarbonyl structural motifs by a phosphorus(III)-mediated reductive condensation of α-keto esters and enolizable carbon pronucleophiles is described. The reaction, which is initiated by Kukhtin-Ramirez addition of commercially available tris(dimethylamino)phosphine to the α-keto ester substrate, proceeds rapidly under mild conditions.
