144108-80-5Relevant articles and documents
A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β
Zhao, Li-Ming,Jin, Hai-Shan,Liu, Jinzhong,Skaar, Todd C.,Ipe, Joseph,Lv, Wei,Flockhart, David A.,Cushman, Mark
, p. 5400 - 5409 (2016/10/24)
The design and synthesis of dual aromatase inhibitors/selective estrogen receptor modulators (AI/SERMs) is an attractive strategy for the discovery of new breast cancer therapeutic agents. Previous efforts led to the preparation of norendoxifen (4) deriva
Preparation of 1-bromo-1-chloro-,1,1-dibromo- or 1,1-dichloroalk-1-enes from ketones
Rezaei, Hadi,Normant, Jean F.
, p. 109 - 112 (2007/10/03)
An efficient three steps process for converting aliphatic ketones to the homologous gem-bromochloro, or gem-dibromo alkenes is presented.