144119-05-1

Basic information

• Product Name: (3S)-1-benzoyl-2-(N-1'(R)-phenylethyl)-amino-3-ethylcyclohexene
• CAS NO: 144119-05-1
• Molecular Weight: 333.473
• Mol File: 144119-05-1.mol

Chemical Properties

• CAS DataBase Reference: (3S)-1-benzoyl-2-(N-1'(R)-phenylethyl)-amino-3-ethylcyclohexene(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-1-benzoyl-2-(N-1'(R)-phenylethyl)-amino-3-ethylcyclohexene(144119-05-1)
• EPA Substance Registry System: (3S)-1-benzoyl-2-(N-1'(R)-phenylethyl)-amino-3-ethylcyclohexene(144119-05-1)

Safety Data

• Hazardous Substances Data: 144119-05-1(Hazardous Substances Data)

Upstream product

• 75-03-6 ethyl iodide 
• 144118-99-0 (R)-1-benzoyl-2--aminocyclohexene 

Relevant articles and documents

Stereoselective Alkylation of Cyclic and Acyclic Chiral β-Enamino Ketones Lithium Dianions: Synthesis of Either (R)- or (S)-Chiral 1,3-Diketones.

The synthesis of either (R)- or (S)-chiral 1,3-diketones through asymmetric γ alkylation reaction of cyclic and acyclic chiral β-enamino ketones was here performed.The alkylation takes place with good yields and high d.e. in HMPA/THF.Both the pure enantiomers of 1,3-diketones can be formed by simple hydrolysis of the epimeric β-enamino ketones obtained with this method, choosing the suitable synthetic strategies.An explanation of the asymmetric induction was proposed.

Stereoselective carbon-carbon bond formation: γ-Alkylation of lithium dianion of chiral cyclic β-enamino ketones

The γ-alkylation of the chiral β-enamino ketones (1) has been obtained with good yields and d.e. on the si face of the lithium dianion intermediate.