144167-60-2

Upstream product

• 144167-32-8 N-(2-mesyloxyphenyl)-α-carbethoxyamidine 
• 10468-46-9 N-(4-bromophenyl)hydroxylamine 
• 144167-25-9 α-amino-α-carbethoxy-N-phenylnitrone 
• 124-63-0 methanesulfonyl chloride 
• 144167-28-2 α-amino-α-carbethoxy-N-(4-bromophenyl)-nitrone 

Relevant academic research and scientific papers

Reactions of hydroxylamines with ethyl cyanoformate. Preparation of aminonitrones and their synthetic applications

The reaction of hydroxylamines with ethyl cyanoformate 1 leads to the formation of carbethoxyamino nitrones. 2. UV spectroscopy provided information that suggested the nitrone structure for these compounds in solution. X-ray analysis of 2a confirmed that it exists entirely in the nitrone form in the solid state. These nitrones are shown to be excellent starting materials for a variety of nitrogen containing compounds, namely, imidazoles, benzimidazoles, benzimidazolones, oxadiazolones, N-arylamidines and quinoxalone.