144219-69-2

Upstream product

• 144219-64-7 3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydro-5-indole-2-propionate 
• 6116-76-3 3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydroindole 
• 98-09-9 benzenesulfonyl chloride 
• 144219-62-5 1-benzenesulfonyl-3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydroindole 

Downstream Products

• 144219-72-7 N-benzenesulfonyl-3-ethyl-4-hydroxy-2-methyl-1H-4,5,6,7-tetrahydro-5-indole-2'-propionic acid 
• 144219-73-8 N-benzenesulfonyl-3,7-dimethyl-8-ethyl-2-oxo-6H-2,3,3a,4,5,8b-hexahydrofuro<2,3-e>indole 

Relevant academic research and scientific papers

ALKYLATION OF 3-ETHYL-2-METHYL-4-OXO-4,5,6,7-TETRAHYDROINDOLE WITH BROMOESTERS: BENZENESULFONYL AS CONVENIENT NITROGEN PROTECTING GROUP

α-Alkylation of 3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydroindole (3) with bromoesters gives 3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydro-5-indoleacetate (5a), 3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydro-5-indole-2-propionate (5b), and 3-ethyl-2-methyl-