14422-77-6

Basic information

• Product Name: 2-chloro-3-(diethylamino)naphthalene-1,4-dione
• CAS NO: 14422-77-6
• Molecular Formula: C₁₄H₁₄ClNO₂
• Molecular Weight: 263.7195
• Mol File: 14422-77-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 345.6°C at 760 mmHg
• Flash Point: 162.8°C
• Density: 1.27g/cm³
• Vapor Pressure: 6.08E-05mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: 2-chloro-3-(diethylamino)naphthalene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-(diethylamino)naphthalene-1,4-dione(14422-77-6)
• EPA Substance Registry System: 2-chloro-3-(diethylamino)naphthalene-1,4-dione(14422-77-6)

Safety Data

• Hazardous Substances Data: 14422-77-6(Hazardous Substances Data)

Upstream product

• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 121-44-8 triethylamine 
• 109-89-7 diethylamine 

Relevant articles and documents

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NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF

Provided herein are compounds of (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, and prodrugs thereof. Also provided are pharmaceutical compositions and methods involving the inventive compounds for the treatment of proliferative diseases (e.g., cancer (e.g., leukemia, breast cancer, melanoma, metastatic cancer) and diseases associated with inappropriate SET8 activity. Also provided are methods for inhibiting SET8 and methods for labelling SET8.

Naphthoquinone Colouring Matters. Part 6. Colour and Constitution of Electron Donor-substituted 2-Aryl- and 2-Vinyl-1,4-naphthoquinones.

The visible absorption spectroscopic properties of 2-aryl-1,4-naphthoquinones containing amino-groups in the 4'-position of the aryl ring or in the 3-position of the quinonoid ring, and also of the related 2-aminovinyl-1,4-naphthoquinones, are described.P