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4-Methylenepiperidine HCl, also known as 4-Methylenepiperidine hydrochloride, is an organic compound that serves as an essential building block in the synthesis of various pharmaceutical compounds. It is a white crystalline solid with a chemical structure that features a piperidine ring with a methylene group attached to the 4-position. The hydrochloride salt form enhances its solubility and stability, making it a versatile intermediate for chemical reactions.

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  • 144230-50-2 Structure
  • Basic information

    1. Product Name: 4-Methylenepiperidine HCl
    2. Synonyms: 4-Methylenepiperidine HCl;4-Methylenepiperidine hydrochloride;Piperidine, 4-methylene-, hydrochloride;4-methylidenepiperidine hydrochloride
    3. CAS NO:144230-50-2
    4. Molecular Formula: C6H12ClN
    5. Molecular Weight: 133.61918
    6. EINECS: 1592732-453-0
    7. Product Categories: N/A
    8. Mol File: 144230-50-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
    8. Solubility: Chloroform (Slightly), Methanol (Slightly)
    9. Stability: Light Sensitive
    10. CAS DataBase Reference: 4-Methylenepiperidine HCl(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-Methylenepiperidine HCl(144230-50-2)
    12. EPA Substance Registry System: 4-Methylenepiperidine HCl(144230-50-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 144230-50-2(Hazardous Substances Data)

144230-50-2 Usage

Uses

Used in Pharmaceutical Industry:
4-Methylenepiperidine HCl is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its ability to be coupled with aryl halides via Suzuki cross-coupling reactions allows for the creation of benzyl piperidines and related compounds, which are often found in drugs targeting the central nervous system, such as antipsychotics, antidepressants, and anti-anxiety medications.
Additionally, 4-Methylenepiperidine HCl can be utilized in the synthesis of other bioactive molecules, including those with potential applications in the treatment of neurological disorders, pain management, and other therapeutic areas. Its versatility as a building block makes it a valuable asset in the design and development of novel pharmaceutical agents.

Check Digit Verification of cas no

The CAS Registry Mumber 144230-50-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,2,3 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 144230-50:
(8*1)+(7*4)+(6*4)+(5*2)+(4*3)+(3*0)+(2*5)+(1*0)=92
92 % 10 = 2
So 144230-50-2 is a valid CAS Registry Number.

144230-50-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methylidenepiperidine,hydrochloride

1.2 Other means of identification

Product number -
Other names 4-methylidenepiperidine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144230-50-2 SDS

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