144284-91-3Relevant academic research and scientific papers
Synthesis of tetraketones in water and under catalyst-free conditions
Yu, Jian-Jun,Wang, Li-Min,Liu, Jin-Qian,Guo, Feng-Lou,Liu, Ying,Jiao, Ning
supporting information; experimental part, p. 216 - 219 (2011/03/19)
A simple, environmentally friendly, tandem Knoevenagel condensation and Michael addition procedure is reported. The reactions between cyclic-13-diketones and a variety of aldehydes were carried out in water to afford tetraketones (64-99%). In this green synthetic protocol, the solvent water itself catalysed the reaction by hydrogen bonding, thus avoiding the use of any other catalysts to make the work up procedure easier.
New Aspects in the Reaction of Azomethines with Cyclic CH-Acidic Compounds
Hennig, Lothar,Alva-Astudillo, Mario,Mann, Gerhard,Kappe, Thomas
, p. 571 - 580 (2007/10/02)
Treatment of substituted benzylidene anilines 1a - f with cyclic CH-acidic compounds 2a - m in ethanol at room temperature yields in addition/elimination reactions the corresponding arylidene derivatives 4 and the 2:1 adducts 5.The addition products 3, which are formed as intermediates, could not be isolated in any case.The donor/acceptor effect of the substituents on the benzylidene moiety influences to a significant extent the reactivity towards the azomethine carbon. Keywords.Azomethine; CH-Acidic compound; Addition/elimination reaction.
