1443005-07-9Relevant academic research and scientific papers
Thiol-ene click chemistry for the synthesis of highly effective glycosyl sulfonamide carbonic anhydrase inhibitors
Saada, Mohamed-Chiheb,Ombouma, Joanna,Montero, Jean-Louis,Supuran, Claudiu T.,Winum, Jean-Yves
, p. 5699 - 5701 (2013/07/25)
Thiol-ene click chemistry has been applied for obtaining sulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitors incorporating sugar moieties. Most of these new compounds were moderate CA I inhibitors, effective CA II inhibitors, and low nanomolar/subn
