1443247-27-5

Basic information

• Product Name: 1-[5-tert-butyl-2-(4-cyano-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4S)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea
• Synonyms: 1-[5-tert-butyl-2-(4-cyano-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4S)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea
• CAS NO: 1443247-27-5
• Molecular Weight: 588.712
• Mol File: 1443247-27-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[5-tert-butyl-2-(4-cyano-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4S)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[5-tert-butyl-2-(4-cyano-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4S)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea(1443247-27-5)
• EPA Substance Registry System: 1-[5-tert-butyl-2-(4-cyano-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4S)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea(1443247-27-5)

Safety Data

• Hazardous Substances Data: 1443247-27-5(Hazardous Substances Data)

Upstream product

• 23357-52-0 (S)-1,2,3,4-tetrahydronapht-1-yl-amine 
• 1351997-21-1 (1S,4S)-amino-N-(S)-4-hydroxy-1,2,3,4-tetrahydronaphthalen-1-ol 
• 1443242-62-3 2,2,2-trifluoro-N-((1S,4S)-4-hydroxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-acetamide 
• 1443242-57-6 2,2,2-trifluoro-N-[(S)‐4‐carbonyl-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide 
• 59997-51-2 trimethylacetylacetonitrile 
• 1241507-60-7 6-fluoro-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine 
• 1241507-59-4 isobutyric acid N'-(5-fluoro-pyridin-2-yl)-hydrazide 
• 869663-55-8 4-(5-amino-3-(tert-butyl)-1H-pyrazol-1-yl)benzonitrile 
• 1105708-62-0 [5-tert-butyl-2-(4-cyano-phenyl)-2H-pyrazol-3-yl]-carbamic acid 2,2,2-trichloro-ethyl ester 
• 1443247-80-0 (1S,4S)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-ylamine 

Relevant articles and documents

KINASE INHIBITORS

Compounds of formula (I): wherein R2, W, A, Y, and R1 are as defined in the specification, and pharmaceutically acceptable salts thereof, are p38 MAPK inhibitors, and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.