1443256-67-4

Basic information

• Product Name: 1-(1-benzyl-4-methyl-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one
• Synonyms: 1-(1-benzyl-4-methyl-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one
• CAS NO: 1443256-67-4
• Molecular Weight: 321.422
• Mol File: 1443256-67-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(1-benzyl-4-methyl-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-benzyl-4-methyl-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(1443256-67-4)
• EPA Substance Registry System: 1-(1-benzyl-4-methyl-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(1443256-67-4)

Safety Data

• Hazardous Substances Data: 1443256-67-4(Hazardous Substances Data)

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 163271-06-5 4-amino-1-benzyl-4-methylpiperidine 
• 1443256-65-2 (1-benzyl-4-methyl-piperidin-4-yl)-(2-nitro-phenyl)-amine 
• 1443256-66-3 N-(1-benzyl-4-methyl-piperidin-4-yl)-benzene-1,2-diamine 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 1443256-68-5 1-(1-benzyl-4-methyl-piperidin-4-yl)-3-methyl-1,3-dihydro-benzoimidazol-2-one 

Relevant articles and documents

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, X, R1, R2, R3 have meanings given in the description.