1443259-22-0

Basic information

• Product Name: (5R,6R)-6-fluoro-5-{2-fluoro-5-[(3-methoxypyridin-2-yl)amino]phenyl}-5-methyl-5,6-dihydro-2H-1,4-oxazin-3-amine
• Synonyms: (5R,6R)-6-fluoro-5-{2-fluoro-5-[(3-methoxypyridin-2-yl)amino]phenyl}-5-methyl-5,6-dihydro-2H-1,4-oxazin-3-amine
• CAS NO: 1443259-22-0
• Molecular Weight: 348.352
• Mol File: 1443259-22-0.mol

Chemical Properties

• CAS DataBase Reference: (5R,6R)-6-fluoro-5-{2-fluoro-5-[(3-methoxypyridin-2-yl)amino]phenyl}-5-methyl-5,6-dihydro-2H-1,4-oxazin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (5R,6R)-6-fluoro-5-{2-fluoro-5-[(3-methoxypyridin-2-yl)amino]phenyl}-5-methyl-5,6-dihydro-2H-1,4-oxazin-3-amine(1443259-22-0)
• EPA Substance Registry System: (5R,6R)-6-fluoro-5-{2-fluoro-5-[(3-methoxypyridin-2-yl)amino]phenyl}-5-methyl-5,6-dihydro-2H-1,4-oxazin-3-amine(1443259-22-0)

Safety Data

• Hazardous Substances Data: 1443259-22-0(Hazardous Substances Data)

Upstream product

• 24100-18-3 2-bromo-3-methoxypyridine 
• 1443259-43-5 (5R,6R)-5-(5-amino-2-fluorophenyl)-6-fluoro-5-methyl-5,6-dihydro-2H-1,4-oxazin-3-amine 
• 1443259-41-3 (5R,6R)-5-(5-bromo-2-fluorophenyl)-6-fluoro-5-methyl-2,6-dihydro-1,4-oxazin-3-amine 

Relevant articles and documents

5-(3-AMINOPHENYL)-5-ALKYL-5,6-DIHYDRO-2H-[1,4]OXAZIN-3-AMINE DERIVATIVES

The present invention relates to novel 5-(3-aminophenyl)-5-alkyl-5,6-dihydro-2H-[1,4]oxazin-3-amine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The invention is also direct

5-(3-AMINOPHENYL)-5-ALKYL-5,6-DIHYDRO-2H-[1,4]OXAZIN-3-AMINE DERIVATIVES

The present invention relates to novel 5-(3-aminophenyl)-5-alkyl-5,6-dihydro- 2H-[1,4]oxazin-3-amine derivatives as inhibitors of beta-secretase, also known as beta- site amyloid cleaving enzyme, BACE, BACE 1, Asp2, or memapsin2. The invention is also dir