1443296-27-2Relevant academic research and scientific papers
Oxidative Mannich Reactions of Tertiary Amines Using a Cu(II) 2-Quinoxalinol Salen Catalyst
Black, Clayton C.,Gorden, Anne E.V.
, p. 9806 - 9810 (2019)
Oxidative Mannich reactions can be catalyzed using a Cu(II) 2-quinoxalinol salen catalyst and with tert-butyl hydroperoxide (TBHP). Under mild conditions, a range of both cyclic and open chain tertiary amines was tested as substrates, resulting in yields up to 98%.
Simple and sustainable iron-catalyzed aerobic C-H functionalization of N, N-dialkylanilines
Ratnikov, Maxim O.,Xu, Xinfang,Doyle, Michael P.
supporting information, p. 9475 - 9479 (2013/07/19)
Iron(III) chloride catalyzes the aerobic oxidation of tertiary anilines, including tetrahydroisoquinolines, to form reactive iminium ion intermediates that undergo Mannich reactions with silyloxyfurans, nitroalkanes, and other nucleophiles to give the cor
