701-56-4

Basic information

• Product Name: (4-METHOXY-PHENYL)-DIMETHYL-AMINE
• Synonyms: 4-Amino-N,N-dimethylanisole[4-Methoxy-N,N-dimethylaniline];NSC 86670;p-(Dimethylamino)anisole;p-Methoxy-N,N-dimethylaniline;(4-METHOXY-PHENYL)-DIMETHYL-AMINE;N,N-dimethyl-4-anisidine;4-N,N-DIMETHYLAMINOANISOLE;N,N-DIMETHYL-PARA-ANISIDINE
• CAS NO: 701-56-4
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.20562
• Mol File: 701-56-4.mol
• Article Data: 160

Chemical Properties

• Melting Point: 48 °C
• Boiling Point: 239.2°C at 760 mmHg
• Flash Point: 69.5°C
• Appearance: /
• Density: 0.998g/cm³
• Vapor Pressure: 0.0407mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.84±0.12(Predicted)
• CAS DataBase Reference: (4-METHOXY-PHENYL)-DIMETHYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-METHOXY-PHENYL)-DIMETHYL-AMINE(701-56-4)
• EPA Substance Registry System: (4-METHOXY-PHENYL)-DIMETHYL-AMINE(701-56-4)

Safety Data

• Statements: 36/37/38
• Hazardous Substances Data: 701-56-4(Hazardous Substances Data)

Usage

General Description

(4-METHOXY-PHENYL)-DIMETHYL-AMINE, also known as dimethyl(4-methoxyphenyl)amine, is a chemical compound with the molecular formula C9H13NO. It is an amine, which is a type of organic compound that contains a basic nitrogen atom. This particular compound contains a dimethylamino group and a 4-methoxyphenyl group, which makes it useful in various chemical and pharmaceutical applications. It is commonly used as a building block in the synthesis of pharmaceutical drugs and other organic compounds. Additionally, it has been studied for its potential use in medicinal chemistry and drug discovery. Due to its properties and versatility, (4-METHOXY-PHENYL)-DIMETHYL-AMINE plays an important role in the field of organic and medicinal chemistry.

InChI:InChI=1/C9H13NO/c1-10(2)8-4-6-9(11-3)7-5-8/h4-7H,1-3H3

Upstream product

• 160852-85-7 2-[2-(2-methoxyethoxy)ethoxy]ethyl methyl carbonate 
• 104-94-9 4-methoxy-aniline 
• 35466-86-5 (2-methoxy)ethyl methyl carbonate 
• 141814-27-9 2-(2-Methoxyethoxy)ethyl methyl carbonate 
• 104292-31-1 N-benzyl-4-methoxy-N,N-dimethylbenzenaminium bromide 
• 593-91-9 trimethylbismuthine 
• 67-56-1 methanol 
• 17310-99-5 4-methoxy-N,N,N-trimethylbenzenaminium iodide 
• 623-26-7 terephthalonitrile radical anion 
• 34418-89-8 4-methoxy-N,N-dimethylaniline N-oxide 
• 698-69-1 4-chloro-N,N-dimethylaniline 
• 865-33-8 potassium methanolate 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 76259-14-8 2,8-Dichloro-5,11-dimethyl-5,6,11,12-tetrahydro-dibenzo[b,f][1,5]diazocine 
• 76259-09-1 3,8-dimethoxy-5,11-dimethyl-5,6,11,12-tetrahidrodibenzo<1,5>diazocine 
• 85021-24-5 2-Chloro-8-methoxy-5,11-dimethyl-5,6,11,12-tetrahydro-dibenzo[b,f][1,5]diazocine 
• 88825-18-7 Toluene-4-sulfonatebenzyl-(4-methoxy-phenyl)-dimethyl-ammonium; 
• 88801-98-3 Benzenesulfonatebenzyl-(4-methoxy-phenyl)-dimethyl-ammonium; 
• 88801-97-2 4-Chloro-benzenesulfonatebenzyl-(4-methoxy-phenyl)-dimethyl-ammonium; 
• 116015-94-2 [4-(Ethoxycarbonyl-{[(4-methoxy-phenyl)-methyl-amino]-methyl}-amino)-phenyl]-carbamic acid ethyl ester 
• 5466-93-3 diethyl 1,4-phenylenediamine-N,N'-dicarboxylate 
• 6324-63-6 N,N'-bisbenzyloxycarbonyl-p-phenylenediamine 
• 116015-98-6 [4-(Benzyloxycarbonyl-{[(4-methoxy-phenyl)-methyl-amino]-methyl}-amino)-phenyl]-carbamic acid benzyl ester 
• 76259-10-4 N,N-dimethyl-o-acetoxy-p-anisidine 
• 5961-59-1 N-methyl-N-(4-methoxyphenyl)amine 
• 1666-13-3 diphenyl diselenide 
• 80447-99-0 2-(dimethylamino)-5-methoxyphenyl phenyl selenide 

Relevant articles and documents

Perchlorate Esters. 4. Kinetics and Mechanism of the Reactions of Alkyl Perchlorates with N,N-Dimethylanilines in Benzene

The reactions in benzene of methyl, ethyl, and isopropyl perchlorates with N,N-dimethylanilines, to yield precipitates of the quaternary anilinium perchlorate, proceed with second-order kinetics and exhibit a large negative entropy of activation.At 25.0 d

A Mild Heteroatom (O -, N -, and S -) Methylation Protocol Using Trimethyl Phosphate (TMP)-Ca(OH) 2Combination

A mild heteroatom methylation protocol using trimethyl phosphate (TMP)-Ca(OH)2combination has been developed, which proceeds in DMF, or water, or under neat conditions, at 80 °C or at room temperature. A series of O-, N-, and S-nucleophiles, including phenols, sulfonamides, N-heterocycles, such as 9H-carbazole, indole derivatives, and 1,8-naphthalimide, and aryl/alkyl thiols, are suitable substrates for this protocol. The high efficiency, operational simplicity, scalability, cost-efficiency, and environmentally friendly nature of this protocol make it an attractive alternative to the conventional base-promoted heteroatom methylation procedures.

Metal-Free Deoxygenation of Amine N-Oxides: Synthetic and Mechanistic Studies

We report herein an unprecedented combination of light and P(III)/P(V) redox cycling for the efficient deoxygenation of aromatic amine N-oxides. Moreover, we discovered that a large variety of aliphatic amine N-oxides can easily be deoxygenated by using only phenylsilane. These practically simple approaches proceed well under metal-free conditions, tolerate many functionalities and are highly chemoselective. Combined experimental and computational studies enabled a deep understanding of factors controlling the reactivity of both aromatic and aliphatic amine N-oxides.

Fe(III)-catalyzed Oxidative Povarov Reaction with Molecular Oxygen Oxidant

The synthesis of tetrahydroquinoline derivatives from dimethyl anilines and enamides has been developed by Fe(III)-phenanthroline complex under aerobic condition. The oxidation of tertiary anilines involving a single electron transfer of Fe(phen)3(PF6)3 afforded the iminium ion intermediate, which reacted with electron-rich alkenes to build a six-membered N-heterocycles containing quaternary carbon center via the oxidative Povarov reaction process.