144331-18-0Relevant academic research and scientific papers
A stereodivergent chirospecific synthesis of (3R) and (3S) 3-hydroxyaspartates by hydroxylation of aspartate diester enolates
Sardina, F. Javier,Paz, Manuel M.,Fernandez-Megia, Eduardo,De Boer, Richard F.,Alvarez, M. Pilar
, p. 4637 - 4640 (1992)
A chirospecific and stereodivergent synthesis of N-(9-phenylfluorenyl)-3-hydroxyaspartates by hydroxylation of aspartate enolates is described. The stereochemistry of the newly created chiral center is controlled by the nature of the enolate counterion an
On the stereoselectivity of the reaction of N-(9-phenylfluoren-9-yl)aspartate enolates with electrophiles. Synthesis of enantiomerically pure 3-hydroxy-, 3-amino-, and 3-hydroxy-3-methylaspartates
Fernandez-Megia,Paz,Javier Sardina
, p. 7643 - 7652 (2007/10/02)
We have developed efficient and stereoselective preparations of enantiomerically pure (3R)- and (3S)-N-Pf-3-hydroxy- and N-Pf-3-aminoaspartates by reaction of N-Pf-aspartate enolates with electrophilic hydroxylating or aminating reagents. The stereoselect
