1443418-80-1

Basic information

• Product Name: diethyl (2-(pyridin-2-yl)phenyl)phosphonate
• Synonyms: diethyl (2-(pyridin-2-yl)phenyl)phosphonate
• CAS NO: 1443418-80-1
• Molecular Weight: 291.287
• Mol File: 1443418-80-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: diethyl (2-(pyridin-2-yl)phenyl)phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (2-(pyridin-2-yl)phenyl)phosphonate(1443418-80-1)
• EPA Substance Registry System: diethyl (2-(pyridin-2-yl)phenyl)phosphonate(1443418-80-1)

Safety Data

• Hazardous Substances Data: 1443418-80-1(Hazardous Substances Data)

Upstream product

• 1008-89-5 2-phenylpyridine 
• 762-04-9 phosphonic acid diethyl ester 
• 762-04-9 Diethyl phosphonate 
• 6632-88-8 diethyl 1-hydroxy-1-methylethylphosphonate 

Relevant articles and documents

Electrochemical C-H phosphorylation of 2-phenylpyridine in the presence of palladium salts

A new approach was developed to the introduction of the phosphonate group into arylpyridines using 2-phenylpyridine as an example. The approach is the electrochemical oxidation of a mixture of 2-phenylpyridine, diethyl phosphite, and palladium acetate at room temperature. An intermediate dipalladium cyclic complex was isolated that is formed by the ortho-palladation of 2-phenylpyridine and substitution of acetate ions by phosphonate ions. The preparative oxidation of this complex selectively results in the product of the phosphorylation of the C-H bond in 2-phenylpyridine.

Pyridine-directed palladium-catalyzed electrochemical phosphonation of C(sp2)-H bond

A new electrocatalytic method for the phosphonation of 2-phenylpyridine was developed. The joint electrochemical oxidation of a mixture of palladium acetate, 2-phenylpyridine, and H-diethylphosphonate affords the ortho C-H phosphonation product. The elect

Pd(II)-catalyzed phosphorylation of aryl C-H bonds

A Pd(II)-catalyzed C-H phosphorylation reaction has been developed using heterocycle-directed ortho-palladation. Both H-phosphonates and diaryl phosphine oxides are suitable coupling partners for this reaction.