6632-88-8

Basic information

• Product Name: diethyl (2-hydroxypropan-2-yl)phosphonate
• CAS NO: 6632-88-8
• Molecular Formula: C₇H₁₇O₄P
• Molecular Weight: 196.1812
• Mol File: 6632-88-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 261.6°C at 760 mmHg
• Flash Point: 112°C
• Density: 1.098g/cm³
• Vapor Pressure: 0.00163mmHg at 25°C
• Refractive Index: 1.432
• CAS DataBase Reference: diethyl (2-hydroxypropan-2-yl)phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (2-hydroxypropan-2-yl)phosphonate(6632-88-8)
• EPA Substance Registry System: diethyl (2-hydroxypropan-2-yl)phosphonate(6632-88-8)

Safety Data

• Hazardous Substances Data: 6632-88-8(Hazardous Substances Data)

Upstream product

• 67-64-1 acetone 
• 122-52-1 triethyl phosphite 
• 110-89-4 piperidine 
• 108-94-1 cyclohexanone 
• 762-04-9 phosphonic acid diethyl ester 

Downstream Products

• 762-04-9 phosphonic acid diethyl ester 
• 13716-45-5 diethyl trimethylsilyl phosphite 
• 1443418-80-1 diethyl (2-(pyridin-2-yl)phenyl)phosphonate 
• 20170-34-7 diethyl 2-isopropenylphosphonate 

Relevant articles and documents

The preparation of dialkyl 1-hydroxyalkylphosphonates in the reaction of trialkyl phosphites with oxonium salts derived from aldehydes or ketones

The reaction of trialkyl phosphites with aldehydes or ketones in the presence of hydrogen chloride gives dialkyl 1-hydroxyalkylphosphonates via Arbusov-like reaction of oxonium salts derived from aldehydes or ketones. This reaction is a very convenient instant method for the preparation of dialkyl 1-hydroxyalkylphosphonates with a good yield as an alternative to the well-known Abramov reaction. Georg Thieme Verlag Stuttgart.