1443422-65-8Relevant articles and documents
Rhodium catalyzed cyanation of chelation assisted C-H bonds
Chaitanya, Manthena,Yadagiri, Dongari,Anbarasan, Pazhamalai
, p. 4960 - 4963 (2013)
A rhodium-catalyzed cyanation of chelation assisted C-H bonds is described employing N-cyano-N-phenyl-p-methylbenzenesulfonamide as an efficient cyanating reagent. The present method allowed the synthesis of various benzonitirle derivatives in good to excellent yield. A number of chelating groups are also effective in the present cyanation of C-H bonds. In addition, the developed methodology was applied in the formal synthesis of the isoquinoline alkaloid, menisporphine.
Rhodium-Catalyzed Direct C-H Bond Cyanation in Ionic Liquids
Lv, Songyang,Li, Yaling,Yao, Tian,Yu, Xinling,Zhang, Chen,Hai, Li,Wu, Yong
supporting information, p. 4994 - 4997 (2018/08/24)
A Cp?Rh(III)/IL-based direct C-H bond cyanation system was developed for the first time. The system is a mild, efficient, and recyclable method for the synthesis of aryl nitriles. Many different directing groups can be used in this cyanation, and the reaction tolerates a variety of functional groups.
Copper-mediated direct aryl C-H cyanation with azobisisobutyronitrile via a free-radical pathway
Xu, Hao,Liu, Peng-Tang,Li, Yun-Hui,Han, Fu-She
supporting information, p. 3354 - 3357 (2013/07/26)
An unprecedented protocol for the copper-mediated direct cyanation of aryl C-H by employing 2,2′-azobisisobutyronitrile (AIBN) as a free radical "CN" source is presented. The protocol not only provides a more efficient pathway for the synthesis of aryl nitriles in terms of the yields and the loading amount of copper salts but also, more importantly, represents a novel strategy for aryl C-H cyanation via a CN free-radical mechanism as compared to the CN anion-participating protocols often reported.
