144343-84-0Relevant articles and documents
HIGHLY STEREOSELECTIVE SYNTHESIS OF SUBSTITUTED HYDRINDANES RELATED TO THE ANTIEPILEPTIC DRUG TOPIRAMATE
Greco, Michael N.,Maryanoff, Bruce E.
, p. 5009 - 5012 (1992)
Multistep syntheses of two "carbocyclic" analogues 2 and 3 of topiramate (1) were effected with excellent stereocontrol.Two key reactions employed were: deoxygenation-rearrangement of an enone with p-tosylhydrazine and catecholborane (14 --> 15 and 5 -->
