Tetrahedron Letters p. 5009 - 5012 (1992)
Update date:2022-08-03
Topics:
Greco, Michael N.
Maryanoff, Bruce E.
Multistep syntheses of two "carbocyclic" analogues 2 and 3 of topiramate (1) were effected with excellent stereocontrol.Two key reactions employed were: deoxygenation-rearrangement of an enone with p-tosylhydrazine and catecholborane (14 --> 15 and 5 -->
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