1443441-66-4Relevant academic research and scientific papers
Domino Radical Addition/Oxidation Sequence with Photocatalysis: One-Pot Synthesis of Polysubstituted Furans from α-Chloro-Alkyl Ketones and Styrenes
Wang, Shuang,Jia, Wen-Liang,Wang, Lin,Liu, Qiang,Wu, Li-Zhu
supporting information, p. 13794 - 13798 (2016/09/21)
A new domino reaction has been developed that allows the combination of styrenes and α-alkyl ketone radicals to afford a wide array of polysubstituted furans in good to excellent yields under mild and simple reaction conditions. The key to success of this novel protocol is the use of photocatalyst fac-Ir(ppy)3and oxidant K2S2O8. Mechanistic studies by a radical scavenger and photoluminescence quenching suggest that a radical addition/oxidation pathway is operable.
Regioselective Synthesis of Multisubstituted Furans via Copper-Mediated Coupling between Ketones and β-Nitrostyrenes
Ghosh, Monoranjan,Mishra, Subhajit,Hajra, Alakananda
, p. 5364 - 5368 (2015/05/27)
A copper-mediated intermolecular annulation of alkyl ketones and β-nitrostyrenes has been developed for the regioselective synthesis of multisubstituted furan derivatives in good yields. This protocol is applicable to both cyclic and acyclic ketones. (Che
Copper-catalyzed regioselective synthesis of furan via tandem cycloaddition of ketone with an unsaturated carboxylic acid under air
Ghosh, Monoranjan,Mishra, Subhajit,Monir, Kamarul,Hajra, Alakananda
, p. 309 - 314 (2015/01/16)
A catalytic decarboxylative annulation has been developed for the regioselective synthesis of trisubstituted furans by the cycloaddition of ketones with α,β-unsaturated carboxylic acids under ambient air. A library of furan derivatives were obtained in good yields from the readily available substrates in the combination of a catalytic amount of Cu-salt and a stoichiometric amount of water. Water plays a crucial role in this catalytic transformation. This journal is
Synthesis of polysubstituted furans via copper-mediated annulation of alkyl ketones with α,β-unsaturated carboxylic acids
Yang, Yuzhu,Yao, Jinzhong,Zhang, Yuhong
supporting information, p. 3206 - 3209 (2013/07/26)
A novel copper-mediated annulation of alkyl ketones with α,β-unsaturated carboxylic acids has been accomplished. This reaction provides a facile and regio-defined method for the synthesis of 2,3,5-trisubstituted furans from simple chemical reagents.
