1443516-79-7Relevant academic research and scientific papers
Rationally designed multifunctional supramolecular iminium catalysis: Direct vinylogous michael addition of unmodified linear dienol substrates
Gu, Yun,Wang, Yao,Yu, Tian-Yang,Liang, Yong-Min,Xu, Peng-Fei
, p. 14128 - 14131 (2014)
The development of a direct vinylogous Michael addition of linear nucleophilic substrates is a long-standing challenge because of the poor reactivity and the considerable difficulty in controlling regioselectivity. By employing a rationally designed multifunctional supramolecular iminium catalysis strategy, the first direct vinylogous Michael addition of unmodified linear substrates to a,b-unsaturated aldehydes, to afford chiral 1,7-dioxo compounds with good yields and excellent regio-as well as enantioselectivity, has been developed.
Organocatalytic, highly enantioselective vinylogous mukaiyama-michael reaction of acyclic dienol silyl ethers
Gupta, Vaishali,Sudhir, Sai V.,Mandal, Tanmay,Schneider, Christoph
, p. 12609 - 12612 (2013/02/23)
Now also acyclic: The first catalytic, enantioselective, vinylogous Michael reaction of linear, acyclic dienol silyl ethers was achieved. The reaction, based upon the principle of iminium ion catalysis, delivered 1,7-dioxo compounds in one step with good
