144367-23-7Relevant academic research and scientific papers
The catalytic asymmetric aldol reaction of silyl ketene acetals with aldehydes in the presence of a chiral borane complex. Nitroethane as a highly effective solvent for catalytic conditions
Kiyooka, Syun-Ichi,Kaneko, Yuichi,Kume, Ken-Ichi
, p. 4927 - 4930 (2007/10/02)
Catalytic asymmetric aldol reactions of silyl ketene acetals with aldehydes in the presence of 20 mol % of the chiral borane reagent, prepared in situ from the p-nitrobenzenesulfonamide of (S)-valine and BH3-THF complex, gave β-hydroxy carboxylic acid esters in good chemical yields along with excellent enantioselectivity under conditions that employ nitroethane as an effective solvent.
