144397-86-4Relevant academic research and scientific papers
Kinetic resolution of vinyl carbonates through a lipase-mediated synthesis of their carbonate and carbamate derivatives
Pozo,Gotor
, p. 10725 - 10732 (2007/10/02)
Lipase from Candida antarctica was used in the synthesis of different chiral carbonates and carbamates through the enzymic resolution of the starting racemic vinyl carbonates. A striking feature was the changeover of the enantioselectivity with regard to
Vinyl carbonates as novel alkoxycarbonylation reagents in enzymatic synthesis of carbonates
Pozo,Pulido,Gotor
, p. 6477 - 6484 (2007/10/02)
Carbonates could be obtained by enzymatic alkoxycarbonylation from vinyl carbonates, which are easily prepared from vinyl chloroformate. The reaction was catalyzed by Candida antarctica lipases, SP 435 and SP 435 A. The method could be also used for the synthesis of carbamates. When racemic alcohols were used, lipase catalyzed their resolution, and chiral carbonates were obtained with different enantiomeric excesses depending upon the structure of the alcohol.
