1443983-86-5

Basic information

• Product Name: 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol
• Synonyms: 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol;EOS-61765;2-(3-Fluoromethyl-azetidin-1-yl)-ethanol
• CAS NO: 1443983-86-5
• Molecular Formula: C6H12FNO
• Molecular Weight: 133.1639832
• Mol File: 1443983-86-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 201.1±10.0 °C(Predicted)
• Appearance: /
• Density: 1.077±0.06 g/cm3(Predicted)
• PKA: 14.74±0.10(Predicted)
• CAS DataBase Reference: 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol(1443983-86-5)
• EPA Substance Registry System: 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol(1443983-86-5)

Safety Data

• Hazardous Substances Data: 1443983-86-5(Hazardous Substances Data)

Usage

General Description

2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol is a chemical compound with the molecular formula C7H13FNO. 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol is a derivative of azetidine, a saturated heterocyclic organic compound with a four-membered ring. The presence of the fluoromethyl group and the hydroxyl group make it potentially useful in medicinal chemistry, particularly in the development of pharmaceutical drugs. The compound may have potential applications in the treatment of various medical conditions, and further research into its properties and potential uses is ongoing.

Upstream product

• 23147-58-2 glycolaldehyde dimer 
• 540-51-2 2-bromoethanol 

Relevant articles and documents

SELECTIVE ESTROGEN RECEPTOR DEGRADERS

Novel selective estrogen receptor degraders (SERDs) according to the formula: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein either R1 or R2 is independently selected from Cl, F, —CF3

PROCESS FOR THE PREPARATION OF 2-(3-(FLUOROMETHYL)AZETIDIN-1-YL)ETHAN-1-OL

Methods of making 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol 9, an intermediate useful for the synthesis of estrogen receptor modulating compounds are described.

AZETIDINE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.