1443991-55-6

Basic information

• Product Name: 3-phenyl-4-methyl-1-ethoxy-6-iodobenz[c-1,2]oxaphosphinine 1-oxide
• Synonyms: 3-phenyl-4-methyl-1-ethoxy-6-iodobenz[c-1,2]oxaphosphinine 1-oxide
• CAS NO: 1443991-55-6
• Molecular Weight: 300.294
• Mol File: 1443991-55-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-phenyl-4-methyl-1-ethoxy-6-iodobenz[c-1,2]oxaphosphinine 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-4-methyl-1-ethoxy-6-iodobenz[c-1,2]oxaphosphinine 1-oxide(1443991-55-6)
• EPA Substance Registry System: 3-phenyl-4-methyl-1-ethoxy-6-iodobenz[c-1,2]oxaphosphinine 1-oxide(1443991-55-6)

Safety Data

• Hazardous Substances Data: 1443991-55-6(Hazardous Substances Data)

Upstream product

• 673-32-5 1-Phenylprop-1-yne 
• 4546-19-4 ethyl hydrogen phenylphosphonate 
• 1754-49-0 diethyl phenylphosphonate 

Relevant articles and documents

NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF

Provided are a novel phosphinine oxide derivative and a preparation method thereof, and more specifically, the phosphinine oxide derivative includes an oxaphosphinine oxide derivative and an azaphosphinine oxide derivative. The phosphinine oxide derivative according to the present invention may have a pharmacological activity and a physiological activity, and may be used as a basic framework of a natural product and may be used for development of new drug and synthesis of various medical supplies. In addition, according to the preparation method of the phosphinine oxide derivative according to the present invention, various phosphinine oxide derivatives with a high yield may be prepared by a simple synthesis process using an intramolecular annulation between a phosphinic derivative and an alkyne derivative in the presence of a rhodium (Rh) catalyst or a ruthenium (Ru) catalyst and an oxidant.

Synthesis of phosphaisocoumarins through rhodium-catalyzed cyclization using alkynes and arylphosphonic acid monoesters

A rhodium-catalyzed cyclization using alkynes and arylphosphonic acid monoesters for the synthesis of phosphaisocoumarins is reported. A number of arylphosphonic acid monoesters were selectively cyclized in high yields with functional group tolerance. In addition, unsymmetrical alkynes are applied in high regioselectivity.