1444121-89-4

Upstream product

• 21874-45-3 1-(tert-butylcarbamoyl)prop-1-en-2-yl 3,5-diamino-6-chloropyrazine-2-carboxylate 
• 4878-36-8 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid 
• 775530-61-5 3,5-diamino-6-chloro-N-[(methylsulfanyl)methanimidoyl]pyrazine-2-carboxamide 
• 1444123-73-2 C₁₄H₂₀N₂O₃ 
• 1458-01-1 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF

The present invention relates to compounds of general formula (I) and the tautomers and the salts thereof, particularly the pharmaceutically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on epithelial sodium channels, the use thereof for the treatment of diseases, particularly diseases of the lungs and airways.