1444310-03-5Relevant articles and documents
Quinolone analogues 12: Synthesis and tautomers of 2-substituted 4-quinolones and related compounds
Kurasawa, Yoshihisa,Yoshida, Kiminari,Yamazaki, Naoki,Iwamoto, Kotoji,Hamamoto, Yoshihiko,Kaji, Eisuke,Sasaki, Kenji,Zamami, Yoshito
, p. 1323 - 1331 (2013/02/22)
The 4-quinolone-2-carboxylates 4a,b were converted into the 4-quinolone-2-carbohydrazides 5a,b, hydrazones 6,7,10, and related compounds 8,9,11. The 4-methoxyquinoline-2-carboxylate 12 was also transformed into the 4-methoxyquinoline-2-carbohydrazide 13, which was modified to the hydrazone 14 and related compound 15. The antimicrobial activities of compounds 6b and 14 are described together with the 4-oxo and 4-hydroxy tautomers of compounds 4-11 in deuteriodimethyl sulfoxide and deuteriotrifluoroacetic acid.