144434-16-2

Upstream product

• 456-56-4 phenyl trifluoromethylsulfide 
• 120474-86-4 (E)-N-furfurylideneaniline 
• 3237-23-8 N-(2-furylmethylene)aniline 
• 81290-20-2 (trifluoromethyl)trimethylsilane 

Downstream Products

• 144434-19-5 (1S,5S,7S)-3-Phenyl-2,5-bis-trifluoromethyl-10-oxa-3-aza-tricyclo[5.2.1.0^1,5]dec-8-en-4-one 

Relevant academic research and scientific papers

Extending the scope of Ruppert's reagent: Trifluoromethylation of imines

The absence of reactivity of imines towards Ruppert's reagent (CF3SiMe3) could be overcome by the addition of an auxiliary silylating agent to the reaction medium. Under these conditions variously substituted α-trifluoromethylated am

Novel and effective synthesis of trifluoromethylated amines by use of an Et3GeNa/C6H5SCF3 combination

Efficient synthesis of trifluoromethylated amine derivatives by use of an Et3GeNa/C6H5SCF3 combination is described. This reaction proceeded smoothly to give the desired compound in excellent yield.