1444349-03-4

Basic information

• Product Name: C₂₄H₃₇NO₅Si
• Synonyms: C₂₄H₃₇NO₅Si
• CAS NO: 1444349-03-4
• Molecular Weight: 447.647
• Mol File: 1444349-03-4.mol

Chemical Properties

• CAS DataBase Reference: C₂₄H₃₇NO₅Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₃₇NO₅Si(1444349-03-4)
• EPA Substance Registry System: C₂₄H₃₇NO₅Si(1444349-03-4)

Safety Data

• Hazardous Substances Data: 1444349-03-4(Hazardous Substances Data)

Upstream product

• 131685-53-5 (S)-4-benzyl-3-propionyl-2-oxazolidinone 
• 220861-39-2 (R)-3-((tert-butyldimethylsilyl)oxy)pent-4-enal 
• 338957-01-0 (3R)-3-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-4-penten-1-ol 
• 1444348-73-5 (R)-2,2,3,3,9,9,10,10-octamethyl-5-vinyl-4,8-dioxa-3,9-disilaundecane 
• 1355509-62-4 (R)-5-(tert-butyldimethylsilyloxy)pent-1-en-3-ol 

Relevant articles and documents

Convergent and enantioselective total synthesis of (-)-amphidinolide O and (-)-amphidinolide P

A convergent and enantioselective total synthesis of (-)-amphidinolide O (1) and P (2), 15-membered macrolides with seven chiral centers along with many functional groups, is described. The key reactions include enantioselective Brown allylation, anti- and syn-selective aldol reactions, (E)-selective olefin metathesis, conformation-controlled stereoselective epoxidation, and selective introduction of the exomethylene group. Assignments of the absolute stereochemistries of the natural (+)-amphidinolide O (ent-1) and P (ent-2) are also discussed in detail.