144460-18-4

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 130403-84-8 methyl (3S)-3-hydroxy-4-{[(4-methylphenyl)sulfonyl]oxy}butanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 90414-36-1 methyl (3S)-3,4-dihydroxybutyrate 

Downstream Products

• 144460-20-8 ((R)-3-Bromo-1-ethyl-propoxy)-tert-butyl-diphenyl-silane 
• 144460-22-0 [(R)-1-(2-Bromo-ethyl)-butoxy]-tert-butyl-diphenyl-silane 
• 144460-19-5 Toluene-4-sulfonic acid (S)-4-bromo-2-(tert-butyl-diphenyl-silanyloxy)-butyl ester 
• 788792-90-5 [(R)-4-(tert-Butyl-diphenyl-silanyloxy)-hexyl]-triphenyl-phosphonium 

Relevant academic research and scientific papers

Enantiospecific Synthesis of 17- and 18-Hydroxyeicosatetraenoic Acids, Cytochrome P450 Arachidonate Metabolites

The title bioactive eicosanoids were prepared from dimethyl L-malate by a convergent strategy exploiting the differential reactivity of ethereal dialkylcuprates towards tosylates versus bromides.