Enantiospecific Synthesis of 17- and 18-Hydroxyeicosatetraenoic Acids, Cytochrome P450 Arachidonate Metabolites

DOI: 10.1016/S0040-4039(00)61226-1

Source and publish data:

Tetrahedron Letters p. 4893 - 4896 (1992)

Update date:2022-08-03

Topics:

Authors:

Falck, J. R.

Lumin, Sun

Lee, Sang-Gyeong

Heckmann, Bertrand

Mioskowski, Charles

et al. et al.

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Article abstract of DOI:10.1016/S0040-4039(00)61226-1

The title bioactive eicosanoids were prepared from dimethyl L-malate by a convergent strategy exploiting the differential reactivity of ethereal dialkylcuprates towards tosylates versus bromides.

Full text of DOI:10.1016/S0040-4039(00)61226-1

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