144461-19-8 Usage
Uses
Used in Pharmaceutical Production:
1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(R)is utilized as an intermediate in the synthesis of various pharmaceuticals. Its chiral nature allows for the creation of enantiomerically pure compounds, which is crucial for the development of drugs with specific therapeutic effects and reduced side effects.
Used in Cosmetics and Personal Care Products:
In the cosmetics and personal care industry, 1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(R)serves as an ingredient that contributes to the formulation of products with improved texture, stability, and performance. Its ability to participate in chemical reactions facilitates the creation of novel compounds with targeted benefits for skin and hair care.
Used in Organic Synthesis:
As a chiral building block, 1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(R)is employed in organic synthesis for the development of new compounds with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science. Its versatility in reactions makes it a valuable component in the synthesis of enantiomerically pure compounds.
Used in Environmentally Friendly Applications:
Recognized for its safety and eco-friendliness, 1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(R)is used in applications seeking to reduce the environmental impact of chemical processes. It serves as a substitute for more harmful chemicals, contributing to the development of greener products and processes.
In Industrial and Laboratory Settings:
1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(R)is commonly found in industrial and laboratory settings, where it is used for research, development, and production purposes. Its presence in these environments underscores the need for proper handling and storage to ensure safety and prevent potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 144461-19-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,4,6 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 144461-19:
(8*1)+(7*4)+(6*4)+(5*4)+(4*6)+(3*1)+(2*1)+(1*9)=118
118 % 10 = 8
So 144461-19-8 is a valid CAS Registry Number.
144461-19-8Relevant articles and documents
Synthesis of acyclic nucleoside derivatives
-
, (2008/06/13)
Methods and novel intermediates of the formula: wherein R6 and R7 are lower alkyl or benzyl or R6 and R7 taken together are —CH2CH2—, —CH2CH2CH2— or —CH2CH2CH2CH2CH2—, R8 is C1-C21 alkyl or a C2-C21 monounsaturated alkenyl, which may optionally be substituted with substitution substituents independently selected from the group consisting of hydroxy, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkoxy C1-C6 alkyl, C1-C6 alkanoyl, amino, halo, cyano, azido, oxo, mercapto and nitro, and R9 is an alcohol protecting group. The intermediates are useful for the preparation of acyclic nucleoside derivatives of the formula: where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a —C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.
Synthesis of optically active nucleoside analogs containing 2,3- dideoxyapiose in the presence of a catalytic amount of trimethylsilyl iodide
Ohsawa,Shiozawa,Achiwa,Terao
, p. 1906 - 1909 (2007/10/02)
Optically pure (R)-4,4-diethoxy-2-(hydroxymethyl)butyl acetate (1) was synthesized enantioselectively by lipase-catalyzed transesterification from 4,4-diethoxy-2-(hydroxymethyl)butanol. Coupling of silylated nucleobases and 2-O-acetyl-5-O-pivaloyl-(3S)-2,
