144465-19-0

Upstream product

• 67-56-1 methanol 
• 7706-60-7 3-(3,4-dimethoxy-phenyl)-crotonic acid ethyl ester 
• 5927-18-4 trimethyl phosphonoacetate 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 

Downstream Products

• 222312-35-8 3-(3,4-dimethoxy-phenyl)-butyric acid methyl ester 
• 181222-28-6 4-(3-azido-1-methylpropyl)-1,2-dimethoxybenzene 
• 222312-26-7 4-(3-azido-1,3-dimethylbutyl)-1,2-dimethoxybenzene 
• 27877-66-3 4-(3,4-dimethoxyphenyl)butan-1-ol 
• 7706-87-8 4-(3,4-dimethoxy-phenyl)-5H-furan-2-one 

Relevant academic research and scientific papers

Hypervalent iodine(III)-induced intramolecular cyclization reaction of substituted phenol ethers with an alkyl azido side-chain: A novel and efficient synthesis of quinone imine derivatives

Novel and efficient syntheses of quinone imine ketals (2aj) and quinone imines (4ah) from substituted phenol ethers (1ak) bearing an alkyl azido side-chain using the combination of hypervalent iodine(III) reagent, phenyliodine(III) bis(trifluoroacetate) (PIFA) and trimethylsilyl trifluoromethanesulfonate (TMSOTf), have been developed.

Simple preparation of 4-aryl- and 4-alkyl-2(5H)-furanones from β-substituted crotonic esters

Treatment of β-aryl- or β-alkylcrotonic esters with selenium dioxide in acetic acid in the presence of a catalytic amount of perchloric acid gave 4-substituted 2(5H)-furanones in moderate to good yields.