144479-49-2

Upstream product

• 100-16-3 4-nitrophenylhydrazone 
• 105051-44-3 3-(β-chloropropionyl)-1-(4-nitrophenyl)formamidrazone 
• 105072-32-0 5-(2-Chloro-ethyl)-1-(4-nitro-phenyl)-1H-[1,2,4]triazole 

Relevant academic research and scientific papers

Efficient syntheses of ω-chloro-, ω-imido- and ω-aminoalkyl-1,2,4-triazoles from N-acyl-formamidinium salts or N-acylformamides and hydrazines

ω-Halo and ω-amidoalkylcyanides 1 are transformed to ω-functionalized N-acylformamidinium salts 4 or formamide 6a by HCl catalyzed addition of chloromethylene iminium salts, derived from formamides 2 and POCl3. Advantageously, β-halo-propionyl-