144501-27-9Relevant articles and documents
Inhibitors of cholesterol biosynthesis. 1. 3,5-dihydroxy-7-(N-imidazolyl)- 6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors
Chan,Bailey,Hartley,Hayman,Hutson,Inglis,Jones,Keeling,Kirk,Lamont,Lester,Pritchard,Ross,Scicinski,Spooner,Smith,Steeples,Watson
, p. 3646 - 3657 (2007/10/02)
3,5-Dihydroxy-7-(N-imidazolyl)heptanoates 4 and the corresponding heptenoates 5 were synthesized as novel classes of potent HMG-CoA reductase (HMGR) inhibitors in which members of the latter series possess enzyme inhibitory activity greater than that of l