144514-38-5 Usage
General Description
3-(4-Acetyl-piperazin-1-yl)-4-chloroaniline is a chemical compound containing an acetyl-piperazinyl group and a chloroaniline group. It is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. The acetyl-piperazinyl group is a commonly used building block in drug design, while the chloroaniline group is frequently used as a precursor in the synthesis of dyes and pigments. Due to its structure and functional groups, 3-(4-Acetyl-piperazin-1-yl)-4-chloroaniline has the potential to be used in a wide range of applications, including pharmaceutical, chemical, and material industries. It is important to handle this chemical with care, as it may pose health and environmental risks if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 144514-38-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,5,1 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 144514-38:
(8*1)+(7*4)+(6*4)+(5*5)+(4*1)+(3*4)+(2*3)+(1*8)=115
115 % 10 = 5
So 144514-38-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H16ClN3O/c1-9(17)15-4-6-16(7-5-15)12-8-10(14)2-3-11(12)13/h2-3,8H,4-7,14H2,1H3
144514-38-5Relevant articles and documents
STUDIES ON PYRIDONECARBOXYLIC ACIDS. 1. SYNTHESIS AND ANTIBACTERIAL EVALUATION OF 7-SUBSTITUTED-6-HALO-4-OXO-4H-THIAZETOQUINOLINE-3-CARBOXYLIC ACIDS
Segawa, Jun,Kitano, Masahiko,Kazuno, Kenji,Matsuoka, Masato,Shirahase, Ichiro,et al.
, p. 4727 - 4738 (2007/10/02)
A series of thiazetoquinoline-3-carboxylic acids and their esters were prepared and evaluated for antibacterial activity.The derivatives with a hydrogen or methyl group at C-1, fluorine at C-6, and piperazinyl or 4-methyl-1-piperazinyl group at C-7 showed superior in vitro antibacterial activity, and the derivatives with 4-methyl-1-piperazinyl group at C-7 had potent in vivo activity.Compound 29a (NM394) showed excellent in vitro antibacterial activity and low toxicity but poor absorption from the gastrointestinal tract.Compound 29ee (NM441), an N- derivative of 29a, was found to possess a favorable pharmacokinetic profile and oral activity superior to that of ciprofloxacin in experimental animals.