144534-29-2Relevant academic research and scientific papers
REACTION OF DIMETHYLAMINOETHYL DERIVATIVES OF 1-BENZYLIDENISOINDOLIN-3-ONE WITH EPOXIDES
Proksa, Bohumil,Steiner, Bohumil,Uhrinova, Stanislava,Koos, Miroslav
, p. 1516 - 1520 (1992)
Derivatives of 1-(2-(2-dimethylaminoethyl)benzyliden)isoindolin-3-one underwent deamination on reaction with epoxides under mild conditions.Amide group of the substrate reacted slower with epoxide than the dimethylamino grouping whilst the alkanolamide was formed with a great excess of the epoxide only.Of epoxides used in the reaction 1,2-epoxy-3-phenoxypropane, 3-decyloxy-1,2-epoxypropane and 3-chloro-1,2-epoxypropane, the first was found to react most rapidly.
