144535-02-4

Upstream product

• 144534-96-3 (2S,4S,5S,6R,8R,9S)-9-Benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-8-ethyl-2-((4S,5S)-5-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-5-(4-methoxy-benzyloxy)-4,6-dimethyl-undecan-4-ol 
• 144534-95-2 (2S,5S,6R,8R,9S)-9-Benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-8-ethyl-2-((4S,5S)-5-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-5-(4-methoxy-benzyloxy)-6-methyl-undecan-4-ol 
• 144534-97-4 Methanesulfonic acid (1S,2R,4R,5S)-5-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-4-ethyl-1-[(1S,3S)-3-((4S,5S)-5-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-1-hydroxy-1-methyl-butyl]-2-methyl-heptyl ester 
• 173044-09-2 Acetic acid (1R,2R,4R,5S)-5-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-1-{(2S,4S,5S)-5-[(S)-1-(tert-butyl-dimethyl-silanyloxymethyl)-propyl]-2,4-dimethyl-tetrahydro-furan-2-yl}-4-ethyl-2-methyl-heptyl ester 
• 173044-10-5 Acetic acid (1R,2R,4R,5S)-5-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-4-ethyl-1-[(2S,4S,5S)-5-((R)-1-formyl-propyl)-2,4-dimethyl-tetrahydro-furan-2-yl]-2-methyl-heptyl ester 
• 173044-08-1 (1R,2R,4R,5S)-5-Benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-1-{(2S,4S,5S)-5-[(S)-1-(tert-butyl-dimethyl-silanyloxymethyl)-propyl]-2,4-dimethyl-tetrahydro-furan-2-yl}-4-ethyl-2-methyl-heptan-1-ol 
• 144535-00-2 Acetic acid (1R,2R,4R,5S)-5-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-4-ethyl-1-[(2S,4S,5S)-5-((S)-1-hydroxymethyl-propyl)-2,4-dimethyl-tetrahydro-furan-2-yl]-2-methyl-heptyl ester 
• 173044-03-6 (1R,2R,4R,5S)-5-Benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-4-ethyl-1-[(2S,4S,5S)-5-((S)-1-hydroxymethyl-propyl)-2,4-dimethyl-tetrahydro-furan-2-yl]-2-methyl-heptan-1-ol 
• 173044-02-5 (2S,3S,4S)-5-{(2R,3R)-3-[(1R,3R,4S)-4-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-3-ethyl-1-methyl-hexyl]-2-methyl-oxiranyl}-2-ethyl-4-methyl-pentane-1,3-diol 
• 144534-80-5 (2S,3R,5R,6S)-6-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-5-ethyl-2-(4-methoxy-benzyloxy)-3-methyl-octanal 
• 152934-39-9 (2S)-2-<(4S,5S)-5-Ethyl-2,2-dimethyl-1,2-dioxan-4-yl>propan-1-ol 
• 144535-02-4 (R)-4-[(2S,4S,5S,3'R,5'R)-5'-((S)-1-Benzyloxy-propyl)-5'-ethyl-2'-hydroxy-2,4,3'-trimethyl-octahydro-[2,2']bifuranyl-5-yl]-hexan-3-one 
• 144534-92-9 (4R,5S)-5-Ethyl-4-((R)-2-iodo-1-methyl-ethyl)-2,2-dimethyl-[1,3]dioxane 
• 144535-01-3 (1R,2R,4R,5S)-5-Benzyloxy-4-ethyl-1-[(2S,4S,5S)-5-((S)-1-ethyl-2-hydroxy-butyl)-2,4-dimethyl-tetrahydro-furan-2-yl]-2-methyl-heptane-1,4-diol 

Downstream Products

• 55898-33-4 ((2S,3R,5S,6S)-6-{(1S,2R,3S,5R)-5-[(2S,4S,5S,2'R,3'R,5'R)-5'-Ethyl-2'-hydroxy-5'-((S)-1-hydroxy-propyl)-2,4,3'-trimethyl-octahydro-[2,2']bifuranyl-5-yl]-2-hydroxy-1,3-dimethyl-4-oxo-heptyl}-2-hydroxy-3,5-dimethyl-tetrahydro-pyran-2-yl)-acetic acid 
• 55898-33-4 ((2S,3R,5S,6S)-6-{(1S,2S,3R,5R)-5-[(2S,4S,5S,2'R,3'R,5'R)-5'-Ethyl-2'-hydroxy-5'-((S)-1-hydroxy-propyl)-2,4,3'-trimethyl-octahydro-[2,2']bifuranyl-5-yl]-2-hydroxy-1,3-dimethyl-4-oxo-heptyl}-2-hydroxy-3,5-dimethyl-tetrahydro-pyran-2-yl)-acetic acid 
• 55898-33-4 ((2S,3R,5S,6S)-6-{(1S,2R,3R,5R)-5-[(2S,4S,5S,2'R,3'R,5'R)-5'-Ethyl-2'-hydroxy-5'-((S)-1-hydroxy-propyl)-2,4,3'-trimethyl-octahydro-[2,2']bifuranyl-5-yl]-2-hydroxy-1,3-dimethyl-4-oxo-heptyl}-2-hydroxy-3,5-dimethyl-tetrahydro-pyran-2-yl)-acetic acid 
• 55898-33-4 Lysocellin 
• 144535-03-5 <4R,4(2S,3S,5R),5<(2RS,3R,5R),5(1S)>>-4-<5-<5-(1-benzyloxy)propyl-5-ethyl-2-methoxy-3-methyltetrahydrofuran-2-yl>-3,5-dimethyltetrahydrofuran-2-yl>hexan-3-one 

Relevant academic research and scientific papers

Stereoselective total synthesis of lysocellin, the representative polyether antibiotic of the lysocellin family. Part 2. Synthesis of C10-C23 subunit via construction of two rings (B and C) and its condensation with C1-C9 subunit to achieve the total synthesis of lysocellin

Stereoselective total synthesis of lysocellin (1), a representative polyether antibiotic, was achieved via coustruction of substituted tetrahydrofuran and γ-lactol rings and final aldol condensation.

Total Synthesis of the Polyether Antibiotic Lysocellin. 2. Stereocontrolled Synthesis of the C10-C23 Fragment and Its Aldol Condensation with the C1-C9 Fragment to Complete the Total Synthesis of Lysocellin

The C10-C23 ethyl ketone (4) was synthesized via coupling of the C16-C23 aldehyde (3) with the C11-C15 fragment (8), and subjected to the aldol reaction with the C1-C9 aldehyde (2) to complete the first stereoselective synthesis of the polyether antibioti