1445578-67-5

Basic information

• Product Name: C₄₃H₆₂N₄O₇S₂Si
• CAS NO: 1445578-67-5
• Molecular Weight: 839.205
• Mol File: 1445578-67-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₃H₆₂N₄O₇S₂Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₃H₆₂N₄O₇S₂Si(1445578-67-5)
• EPA Substance Registry System: C₄₃H₆₂N₄O₇S₂Si(1445578-67-5)

Safety Data

• Hazardous Substances Data: 1445578-67-5(Hazardous Substances Data)

Upstream product

• 1429340-64-6 C₃₉H₅₄N₄O₇ 
• 221186-79-4 (+)-(R)-tert-butyl 1-[(S)-2-amino-3-phenylpropanoyl]pyrrolidine-2-carboxylate 
• 162757-06-4 Z-L-Phe-D-Pro-OtBu 
• 2812-46-6 L-proline t-butyl ester 
• 1161-13-3 N-Cbz-L-Phe 
• 1429340-60-2 C₂₂H₃₂N₂O₅ 
• 84120-87-6 α-methyl-DL-phenylalanine methyl ester hydrochloride 
• 1037074-43-3 (-)-(2S,4R)-3-benzoyl-4-benzyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one 
• 92136-57-7 (S)-2-tert-butoxycarbonylamino-hex-5-enoic acid methyl ester 
• 1247052-81-8 (-)-(R)-S-3-(tert-butyldimethylsilyloxy)-2-oxobutyl O-ethyl carbonodithioate 
• 1429340-67-9 (-)-(3S,6R,9S,14aR)-6,9-dibenzyl-3-(but-3-enyl)-6-methyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone 
• 208522-13-8 (S)-2-N-(tert-butoxycarbonyl)-2-amino-5-hexenoic acid 
• 832151-92-5 (R)-1-chloro-3-(tert-butyldimethylsilyloxy)butan-2-one 

Downstream Products

• 561044-87-9 (-)-(3S,6R,9S,14aR)-6,9-dibenzyl-3-[(R)-7-hydroxy-6-oxooctyl]-6-methyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone 
• 1445578-66-4 C₄₀H₅₈N₄O₆Si 

Relevant articles and documents

Flexible synthesis and evaluation of diverse anti-apicomplexa cyclic peptides

A modular approach to synthesize anti-Apicomplexa parasite inhibitors was developed that takes advantage of a pluripotent cyclic tetrapeptide scaffold capable of adjusting appendage and skeletal diversities in only a few steps (one to three steps). The diversification processes make use of selective radical coupling reactions and involve a new example of a reductive carbon-nitrogen cleavage reaction with SmI2. The resulting bioactive cyclic peptides have revealed new insights into structural factors that govern selectivity between Apicomplexa parasites such as Toxoplasma and Plasmodium and human cells.