144562-73-2Relevant academic research and scientific papers
Structure-activity relationships of (E)-3-(1,4-benzoquinonyl)-2-[(3- pyridyl)alkyl]-2-propenoic acid derivatives that inhibit both 5-lipoxygenase and thromboxane A2 synthetase
Hibi, Shigeki,Okamoto, Yasushi,Tagami, Katsuya,Numata, Hirotoshi,Kobayashi, Naoki,Shinoda, Masanobu,Kawahara, Tetsuya,Harada, Koukichi,Miyamoto, Kaname,Yamatsu, Isao
, p. 3148 - 3157 (2007/10/03)
As part of our research for the development of novel antiinflammatory drug candidates, we have designed and synthesized a series of (E)-3-(1,4- benzoquinonyl)-2-[(3-pyridyl)alkyl]-2-propenoic acid derivatives as dual inhibitors of 5-lipoxygenase (5-LO) an
