144563-06-4

Upstream product

• 144562-69-6 7-Pyridin-3-yl-2-[1-(2,3,6-trimethoxy-4,5-dimethyl-phenyl)-meth-(E)-ylidene]-heptanoic acid ethyl ester 
• 144563-18-8 ethyl 2-diethylphosphono-7-(3-pyridyl)heptanoate 
• 66890-58-2 2,5-dimethoxy-3,4-dimethylphenol 
• 180778-12-5 2,3,6-Trimethoxy-4,5-dimethyl-benzaldehyde 
• 1027939-42-9 2-Hydroxy-3,6-dimethoxy-4,5-dimethyl-benzaldehyde 
• 150057-34-4 3-(5-Chloro-pentyl)-pyridine 
• 84200-03-3 5-pyridin-3-yl-pentan-1-ol 
• 144562-87-8 (E)-3-(2,5,6-trimethoxy-3,4-dimethylphenyl)-2-[5-(3-pyridyl)pentyl]-2-propenoic acid 

Relevant academic research and scientific papers

Structure-activity relationships of (E)-3-(1,4-benzoquinonyl)-2-[(3- pyridyl)alkyl]-2-propenoic acid derivatives that inhibit both 5-lipoxygenase and thromboxane A2 synthetase

As part of our research for the development of novel antiinflammatory drug candidates, we have designed and synthesized a series of (E)-3-(1,4- benzoquinonyl)-2-[(3-pyridyl)alkyl]-2-propenoic acid derivatives as dual inhibitors of 5-lipoxygenase (5-LO) an

Quinone derivatives

The present invention is a quinone derivative which exhibits excellent therapeutic activity represented by the general formula (I) or a pharmacologically acceptable salt thereof: STR1 wherein A stands for a group represented by the formula: STR2 (wherein