1445873-56-2

Basic information

• Product Name: C₉H₁₇N₂O₂^(1-)*Na⁽¹⁺⁾
• CAS NO: 1445873-56-2
• Molecular Weight: 208.236
• Mol File: 1445873-56-2.mol

Chemical Properties

• CAS DataBase Reference: C₉H₁₇N₂O₂^(1-)*Na⁽¹⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: C₉H₁₇N₂O₂^(1-)*Na⁽¹⁺⁾(1445873-56-2)
• EPA Substance Registry System: C₉H₁₇N₂O₂^(1-)*Na⁽¹⁺⁾(1445873-56-2)

Safety Data

• Hazardous Substances Data: 1445873-56-2(Hazardous Substances Data)

Upstream product

• 146504-07-6 tert-butyl ((1R,2R)-2-aminocyclohexyl)carbamate 

Relevant articles and documents

Synthesis, cytotoxicity, and apoptosis induction study of antitumor dinuclear platinum(II) complexes

Five novel dinuclear platinum(II) complexes with a new chiral ligand, 3-(2-amino-cyclohexylamino)-propionic acid (HP), were designed, prepared and spectrally characterized. The in vitro cytotoxicities of these compounds were evaluated against the HepG-2, MCF-7, A549, and HCT-116 cell lines. The results indicated that all compounds showed cytotoxicity towards the HepG-2 cell line. Particularly, complex X5, which has SO 42- as a bridge, exhibited better cytotoxicity than carboplatin or oxaliplatin against all selected cell lines. Moreover, double dyeing flow cytometric resection indicated that the target compounds inhibited tumor cell growth by inducing apoptosis. Five novel dinuclear platinum(II) complexes with a new chiral ligand, 3-(2-amino- cyclohexylamino)-propionic acid, were designed. The in vitro cytotoxicity results of these compounds against the HepG-2, MCF-7, A549, and HCT-116 cell lines indicated that all compounds showed cytotoxicity towards the HepG-2 cell line. Particularly, complex X5, which has SO 42- as a bridge, exhibited better cytotoxicity than carboplatin or oxaliplatin against all selected cell lines. Copyright