1446090-67-0

Basic information

• Product Name: 4-chloro-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile
• CAS NO: 1446090-67-0
• Molecular Weight: 306.175
• Mol File: 1446090-67-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile(1446090-67-0)
• EPA Substance Registry System: 4-chloro-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile(1446090-67-0)

Safety Data

• Hazardous Substances Data: 1446090-67-0(Hazardous Substances Data)

Upstream product

• 1374790-60-9 5-(4-chlorophenyl)-3,4-dihydro-4-oxothieno[2,3-d]pyrimidine-6-carboxamide 
• 1335000-74-2 5-amino-3-(4-chlorophenyl)thiophene-2,4-dicarboxamide 
• 139260-20-1 5-amino-3-(4-chlorophenyl)thiophene-2,4-dicarbonitrile 

Downstream Products

• 1446090-53-4 5-(4-chlorophenyl)-4-(diethylamino)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-54-5 5-(4-chlorophenyl)-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-55-6 5-(4-chlorophenyl)-4-morpholinothieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-56-7 5-(4-chlorophenyl)-4-(piperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-57-8 ethyl 4-(5-(4-chlorophenyl)-6-cyanothieno[2,3-d]pyrimidin-4-yl)piperazine-1-carboxylate 
• 1446090-58-9 5-(4-chlorophenyl)-4-(4-(2,3-dichlorophenyl)piperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-59-0 4-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-60-3 5-(4-chlorophenyl)-4-(2,3-dihydrobenzo[b][1,4]dioxin-3-yl)(piperazin-1-yl)methanone-thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-61-4 4-(benzylamino)-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-62-5 4-(2-chlorophenylamino)-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-63-6 4-(3-chlorophenylamino)-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-64-7 4-(o-tolylamino)-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile 
• 1446090-65-8 4-(m-tolylamino)-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine-6-carbonitrile 

Relevant articles and documents

Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6- carbonitrile derivatives acting as antimicrobial agents

Thermal selective reactions were studied on oxothieno[2,3-d]pyrimidine-6- carboxamide 3 with POCl3 and PCl5. At 25-50 C, the C 7-amide rearranges to nitrile furnished compound 4 in 85-90% yield, while at 80-110 C furnished