1446099-54-2

Basic information

• Product Name: (4-(2-chloroethoxy)phenyl)(2-fluorophenyl)methanone
• CAS NO: 1446099-54-2
• Molecular Weight: 278.71
• Mol File: 1446099-54-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-(2-chloroethoxy)phenyl)(2-fluorophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(2-chloroethoxy)phenyl)(2-fluorophenyl)methanone(1446099-54-2)
• EPA Substance Registry System: (4-(2-chloroethoxy)phenyl)(2-fluorophenyl)methanone(1446099-54-2)

Safety Data

• Hazardous Substances Data: 1446099-54-2(Hazardous Substances Data)

Upstream product

• 107-04-0 1-Bromo-2-chloroethane 
• 101969-75-9 (2-fluorophenyl)(4-hydroxyphenyl)methanone 

Downstream Products

• 1446099-44-0 (R)-(2-fluorophenyl)(4-(2-(2-methylpyrrolidin-1-yl)ethoxy)phenyl)methanone 

Relevant articles and documents

Synthesis and biological evaluation of XB-1 analogues as novel histamine H3 receptor antagonists and neuroprotective agents

A novel class of H3 receptor antagonists, XB-1 analogues based on benzophenone or oxydibenzene scaffolds were synthesized, and their biological activities were evaluated to determine their in vitro neuroprotective effects against Aβ25-35-induced damage in primary cortical neurons and against glutamate-induced neuronal injury in primary cerebellar granule neurons. The results indicated that all of the tested analogues displayed neuroprotective activity at 0.1 μM or 1 μM. These findings may provide new insights into the development of novel promising H3 receptor antagonists with potential neuroprotective activity.